What can contaminate a cleanroom?

没有人能保证一个完美的、无污染的洁净室。However by adhering to room pressure requirements, proper gowning procedures and by understanding the origins of the contaminants, users can minimize contamination risk to ensuresafe testing and manufacturing environment. These are some of the things you may not have realized can compromise a cleanroom, and some possible ways to reduce the contamination of the source.

1. Personnel

Personnel are considered to be the biggest threat and the highest source for contaminant material, accounting for about 75% to 80% of particles found in cleanroom inspections. Personnel (Figure 1) introduce particles through skin flakes, oil, hair, yeast and movement, while bringing in external particles from cosmetics, perfume, deodorants, lotions, and clothing (lint, fibers).

2. Manufacturing Equipment

Manufacturing equipment can generate gas, lubricants, emissions, and airborne particles during use. Equipment should be the first thing introduced in a room; evaluated and Material Safety Data Sheet (MSDS) approved for all the materials used in its composition, including any chemicals used by the manufacturer. Sterilization and examination, specific conductivity material, antistatic characteristics, out-gassing properties, and antimicrobial aspects may be required for safe cleaning of the equipment.

3.Tools

污染物可来自日常工具，如普通的家庭或工业清洁产品(扫帚、拖把、抹布)和书写用品(钢笔、铅笔、纸张)。使用经批准的无微粒抹布、拖把、无尘室吸尘器等解决方案对洁净室内物体进行清洁。还应使用特殊的书写材料、经批准的洁净室纸(用密封塑料密封)或电子文档。带有高效微粒空气过滤器的常规真空吸尘器并不是一个可行的选择，因为它们在使用过程中会释放出粒子，效率只有99.96%。

4. Raw Materials/ Products

Products can generate glass flakes, cleanroom debris, and aluminum particles from vial caps. The extent of cleaning varies, depending on the class of cleanroom, the destination of the raw material or product, and the possibility of any cross contamination to other processes. Transport tunnels, hanging shields, nitrogen purged and vacuum processing, Standard Mechanical InterFace, laminar flow stations, or isolation carriers can help reduce risk of product-generated contaminants.

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